Zenyatta and Curlin are heavy favorites in the Breeders’ Cup Ladies Classic and the Breeders’ Cup Classic respectively. The two Classics are the highlights of a 14-race slate spread over two days with $25.5 million in purses up for grabs.

Zenyatta is a perfect 8-for-8 in her career, and if she makes it nine straight against the girls while Curlin struggles on Santa Anita’s synthetic Pro Ride surface in the $5 million Classic, there’s a chance she could ruin Curlin’s shot at becoming the first horse since Cigar in the mid-1990s to win consecutive Horse of the Year awards.

Curlin will try to add to his legacy as one of flat racing’s all-time greats when he attempts to duplicate his victory of last year at rain-soaked Monmouth Park as the Breeders’ Cup 2008 moves to the synthetic track at Santa Anita in sunny Southern California.

Zenyatta is the overwhelming 3-5 favorite in the Ladies Classic and Curlin drew the No. 9 post and was made the early favorite at 7-5. Click here to check out Breeders’ Cup betting odds on other contenders.